Article No
155-98-611
Specifications
| NCBI Number | 12507 |
| Accession Number | P13379 |
| Application | ELISA, FC, ICC, IHC, IP, Multiplex, Neutralization |
| Article No | 155-98-611 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 53-7.3 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/ml |
| Conjugation | PE |
| Description | CD5 Antibody [53-7.3] (PE) |
| Supplier | ProSci |
| Entrez Gene ID | 12507 |
| Format | Liquid |
| Gene Symbol | Cd5 |
| Immunogen | Spleen cells or thymocyte membranes |
| Isotype | IgG2a |
| Notes | CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors. |
| Alias Names | Lyt-1, Ly-1, Lymphocyte antigen 1, Ly-12, Ly-A, T1, Tp67 |
| Previous Article No | 155-98-611-0.1 |
| Product Type | Antibodies Primary |
| Protocol | CD5 Antibody [53-7.3] for use in flow cytometry assays. |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 0.1 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 4°C |
| Substrate / Buffer | Supplied in PBS/NaN3 and a stabilizing agent |
| Technical Specifications | CD5 Antibody [53-7.3] for use in flow cytometry assays. |
| UniProt Number | P13379 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
