Article No
155-96-615
CD273 Recombinant Protein
CD273 Recombinant Protein
Proteins & Peptides
Specifications
| MW | 23.4 kDa |
| NCBI Number | 80380 |
| Accession Number | AAI13679 |
| Application | WB |
| Article No | 155-96-615 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Description | CD273 Recombinant Protein |
| Supplier | ProSci |
| Entrez Gene ID | 80380 |
| Format | Lyophilized |
| Gene Symbol | PDCD1LG2 |
| Notes | Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| Alias Names | PDL2, PD-L2, Butyrophilin B7-DC, CD273, PDCD1 ligand 2, PDCD1L2, PDCD1LG2 |
| Previous Article No | 155-96-615-0.1 |
| Product Type | Proteins & Peptides |
| Protocol | This recombinant protein can be used for WB. For research use only. |
| Purity | >95% |
| Research area | Cell Death |
| Sequence | Leu 20 - Pro 219 |
| Shipping Information | RT |
| Size | 0.1 mg |
| Storage | -20°C, -80°C |
| Substrate / Buffer | PBS, pH 7.4 |
| Technical Specifications | Measured by its binding ability in a functional ELISA. Immobilized rh B7-DC / PD-L2 / CD273 at 1 μg/mL (100 μl/well) can bind rhPDCD-1 with a linear range of 15 - 500 ng/mL. |
| UniProt Number | Q9BQ51 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
