Article No
155-76-022
Specifications
| NCBI Number | 958 |
| Application | FC |
| Article No | 155-76-022 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 5C3 |
| Clone Type | monoclonal |
| Concentration | batch dependent |
| Conjugation | FITC |
| Description | CD40 Antibody [5C3] (FITC) |
| Supplier | ProSci |
| Entrez Gene ID | 958 |
| Format | Liquid |
| Gene Symbol | CD40 |
| Isotype | IgG1 k |
| Notes | The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation. |
| Alias Names | p50, Bp50, CDW40, TNFRSF5, CD40 |
| Previous Article No | 155-76-022-25 |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 25 tests |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| Substrate / Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
| UniProt Number | P25942 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
