Article No
12-1036-100
Parathyroid Hormone (PTH) (N-Terminal)
Recombinant Rabbit Monoclonal Antibody to Parathyroid Hormone (PTH) (N-Terminal)(Clone : PTH/1717R)
Antibodies Primary
Specifications
| Application | IHC |
| Article No | 12-1036-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | PTH/1717R |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Recombinant Rabbit Monoclonal Antibody to Parathyroid Hormone (PTH) (N-Terminal)(Clone : PTH/1717R) |
| Supplier | Abeomics |
| Entrez Gene ID | 5741 |
| Gene Symbol | PTH |
| Immunogen | Recombinant human PTH protein N-terminal fragment (exact sequence is proprietary) |
| Isotype | IgG |
| Keywords | Recombinant rabbit antibodies, Parathyroid Hormone (PTH) (N-Terminal), PTH, 5741, P01270, hPTH, Parathormone, Parathyrin, Parathyroid hormone 1 (PTH1), Parathyroid hormone (PTH), PTH/1717R, Recombinant Rabbit Monoclonal Antibody to Parathyroid Hormone (PTH) (N-Terminal)(Clone : PTH/1717R), Recombinant Rabbit Monoclonal Antibody to Parathyroid Hormone (PTH) (N-Terminal) |
| Notes | Epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. |
| Alias Names | hPTH, Parathormone, Parathyrin, Parathyroid hormone 1 (PTH1), Parathyroid hormone (PTH) |
| Product Type | Antibodies Primary |
| Protocol | Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) |
| Purification | Purified |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 200 µg/ml of Ab purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| UniProt Number | P01270 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
