Article No
12-1006-100
Ep-CAM / CD326 (Epithelial Marker)
Recombinant Mouse Monoclonal Antibody to Ep-CAM / CD326 (Epithelial Marker)(Clone : rMOC-31)
Antibodies Primary
Specifications
| Application | FC, IF, IHC, WB |
| Article No | 12-1006-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | rMOC-31 |
| Clone Type | monoclonal |
| Description | Recombinant Mouse Monoclonal Antibody to Ep-CAM / CD326 (Epithelial Marker)(Clone : rMOC-31) |
| Supplier | Abeomics |
| Entrez Gene ID | 4072 |
| Gene Symbol | EPCAM |
| Immunogen | Neuraminidase treated GLS-1 human small cell lung carcinoma cells |
| Isotype | IgG1 k |
| Keywords | Recombinant mouse antibodies, Ep-CAM / CD326 (Epithelial Marker), EPCAM, 4072, P16422, Adenocarcinoma-associated Antigen, Cell Surface Glycoprotein Trop-1, EGP2, EGP314, EGP40, Epithelial Cell Adhesion Molecule, Epithelial Glycoprotein 314, ESA, KSA, TACD1, TROP1, Tumor-associated Calcium Signal Transducer 1 (TACSTD1), ECS-1, Epidermal Surface Antigen 1, ESA1, FLOT2, Flotillin-2, Membrane Component, Chromosome 17, Surface Marker-1 (M17S1), REG-1, Regg |
| Notes | Binding epitope of this antibody is located in the first EGF-like repeat domain (EGF1) between amino acids 27-59 of Ep-CAM. EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. |
| Alias Names | Adenocarcinoma-associated Antigen, Cell Surface Glycoprotein Trop-1, EGP2, EGP314, EGP40, Epithelial Cell Adhesion Molecule, Epithelial Glycoprotein 314, ESA, KSA, TACD1, TROP1, Tumor-associated Calcium Signal Transducer 1 (TACSTD1), ECS-1, Epidermal Surface Antigen 1, ESA1, FLOT2, F |
| Product Type | Antibodies Primary |
| Protocol | Flow Cytometry (1-2µg/million cells); Immunofluorescence (1-2µg/ml); Western Blot (1-2µg/ml); ,Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes) |
| Purification | Purified |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 200 µg/ml of recombinant MAb purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| UniProt Number | P16422 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
