Article No
10-4111-25
S100A8
Monoclonal Antibody to S100A8 (Clone: ABM4D13)
Antibodies Primary
Specifications
| Application | WB |
| Article No | 10-4111-25 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ABM4D13 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to S100A8 (Clone: ABM4D13) |
| Supplier | Abeomics |
| Entrez Gene ID | 6279 |
| Gene Symbol | S100A8 |
| Immunogen | Full length recombinant S100A8 protein was used as the immunogen for this antibody. |
| Isotype | IgG1 k |
| Keywords | Immunology, S100a8, 20201, P27005, S100a8, Caga, Mrp8, ABM4D13, Monoclonal Antibody to S100A8, human(Clone :ABM4D13), Anti S100A8, human Antibody, S100A8, human Antibody |
| Notes | S100A8 is a low molecular weight (10 kDa) secreted cytoplasmic protein belonging to S100 family of calcium- and zinc-binding protein. S100A8 regulates a number of cellular processes, such as, inflammation, antimicrobial, oxidant-scavenging and apoptosis-inducing activities, cell cycle progression and differentiation, leukocyte arachidonic acid trafficking and metabolism. S100A8 is a homodimer but predominantly remains as heterodimer with S100A9 and the S100A8/S100A9 complex is called as Calprotectin. S100A8 is generally expressed in myeloid cells, neutrophils, monocytes and keratinocytes but high levels are found in the serum sample of patients with inflammatory diseases, such as, rheumatoid, cystic fibrosis, inflammatory bowel disease, systemic lupus erythematosus, progressive systemic sclerosis and many other inflammatory diseases. S100A8 is also associated with Psoriasis (an inflammatory skin disorder characterized by keratinocyte hyperproliferation and altered differentiation). |
| Alias Names | Protein S100-A8, Calgranulin-A, Calprotectin L1L subunit, Leukocyte L1 complex light chain, S100 calcium-binding protein A8 |
| Product Type | Antibodies Primary |
| Protocol | Western blot analysis: 2-4 µg/ml |
| Purification | Protein G Purified |
| Research area | Immunology |
| Shipping Information | Blue Ice |
| Size | 25 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 25 µg in 50 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | P05109 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
