Article No
10-3002-25
TLR6
Monoclonal Antibody to TLR6 (Clone: ABM1B50)
Antibodies Primary
Specifications
| Application | FC, WB |
| Article No | 10-3002-25 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ABM1B50 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to TLR6 (Clone: ABM1B50) |
| Supplier | Abeomics |
| Entrez Gene ID | 10333 |
| Gene Symbol | TLR6 |
| Immunogen | A partial length recombinant TLR6 protein (amino acids 280-512) was used as the immunogen for this antibody. |
| Isotype | IgG1 k |
| Notes | TLR6 (Toll-Like Receptors 6) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR6 forms heterodimers with TLR1 and TLR2, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 in co-operation with TLR6 trigger inflammatory responses via activation of NF-kappaB, which regulates the transcription of inflammatory molecules. TLR6 has emerged as the most potent activator for ZNPs (Zinc Oxide Nanoparticles)-induced inflammatory responses. Upon silencing, TLR6 significantly inhibited the pro-inflammatory cytokine levels, reactive nitrogen species generation and inducible nitric oxide synthase expression. |
| Alias Names | TLR6 |
| Product Type | Antibodies Primary |
| Protocol | Western blot analysis: 2-4 µg/ml; FACS analysis: 0.5-1 µg/10^6 cells |
| Purification | Protein G Purified |
| Research area | Immunology |
| Shipping Information | Blue Ice |
| Size | 25 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 25 µg in 50 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | Q9Y2C9 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
