This product is not available for sale in your country. Please feel free to contact the help desk if you have any questions.
|Country Availability||DK, EE, FI, FO, GL, IS, LT, LV, NO, SE|
|Data Sheet Link||https://www.biossusa.com/store/datasheets/bs-1124R|
|Description||5-HTR1A Polyclonal Antibody|
|Entrez Gene ID||24473|
|Notes||G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.|
|Alias Names||5HT1A; RAT5HT1A; 5-hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; Serotonin receptor 1A; Htr1a|
|Protocol||WB(1:300-1000), IHC-P(1:200-400), IF(IHC-P)(1:50-200)|
|Purification||Purified by Protein A.|
|Source / Host||rabbit|
|Species Reactivity||human, mouse, rat|
|Storage||Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.|
|Technical Specifications||KLH conjugated synthetic peptide derived from rat 5-HTR1A|
|Product Page Updated||2019-01-03T14:43:56.134Z|
The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.