Antibodies Primary

anti-PGRP-L, mAb (45G1)

NEW
anti-PGRP-L, mAb (45G1)

Article No

YIF-LF-MA0135

Application

ELISA, WB

Species Reactivity

human

Size

100 µl

Clone

45G1

Product insert

Suggested protocols

Specifications

Application ELISA, WB
Article No YIF-LF-MA0135
Country Availability SE, FI, DK, NO, IS, EE, LV, LT
Clone 45G1
Clone Type monoclonal
Description anti-PGRP-L, mAb (45G1)
Supplier Adipogen Life Sciences
Format Liquid
Immunogen Peptidoglycan recognition protein (PGRP)-L purified form human protein.
Isotype IgG1 k
Notes Peptidoglycan recognition proteins (PGRPs) are pattern recognition molecules that recognize bacteria and their unique cell wall component, peptidoglycan (PGN). Mammals have four PGRPs, designated in humans PGRP-S(24kDa), PGRP-L(60~65kDa), PGRP-Ialpha(38kDa), and PGRP-Ibeta(44kDa). Human PGRPs are differentially expressed in various tissues and organs: PGRP-S mainly in the bone marrow and Polymorphonuclear leukocyte (PMNs), PGRP-L mainly in the liver, and PGRP-Ia and PGRP-Ib mainly in the esophagus. The function of only one mammalian PGRP, PGRP-S, is currently known. Mouse PGRP-S is present in neutrophils and inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophil antibacterial protein. May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.
Alias Names PGRP-L; PGLYRPL; PGLYRP2; EC=3.5.1.28; N-Acetylmuramoyl-L-Alanine Amidase; Peptidoglycan Recognition Protein 2; Peptidoglycan Recognition Protein Long
Product Type Antibodies Primary
References 1) Zheng-Ming Wang et. al. (2003) J Biol Chem 278 (49): 49044-49052. (General)2) Chao Liu et. al. (2001) J Biol Chem 276(37): 34686-34694. (General)
Research Area Immunology
Size 100 µl
Species Reactivity human
Stability Stable for at least 1 year after receipt when stored at -20°C.
Storage -20°C
Substrate / Buffer Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Technical Specifications Monoclonal Antibody. Recognizes the Human protein. Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. Peptidoglycan recognition proteins (PGRPs) are pattern recognition molecules that recognize bacteria and their unique cell wall component, peptidoglycan (PGN). Mammals have four PGRPs, designated in humans PGRP-S(24kDa), PGRP-L(60~65kDa), PGRP-Ialpha(38kDa), and PGRP-Ibeta(44kDa). Human PGRPs are differentially expressed in various tissues and organs: PGRP-S mainly in the bone marrow and Polymorphonuclear leukocyte (PMNs), PGRP-L mainly in the liver, and PGRP-Ia and PGRP-Ib mainly in the esophagus. The function of only one mammalian PGRP, PGRP-S, is currently known. Mouse PGRP-S is present in neutrophils and inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophil antibacterial protein. May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.
Product Page Updated 2019-07-12T09:17:06.689Z

Shipping info

The delivery time for this item is approximately 5-8 business days. 
If other deviations occur, this will be noted on the order confirmation or communicated via email.
Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.