Antibodies Primary

Anti-5-hydroxymethylcytosine (5hmC) pAb

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Anti-5-hydroxymethylcytosine (5hmC) pAb

Article No

PM077

Application

IP, WB

Size

100 µl

Source / Host

rabbit

Shipping Information

4°C

Product insert

Specifications

Application IP, WB
Article No PM077
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL
Clone Type polyclonal
Description Anti-5-hydroxymethylcytosine (5hmC) pAb
Supplier MBL International Corp.
Immunogen BSA-conjugated 5-hydroxymethylcytidine
Isotype Ig
Notes DNA methylation is one of many critical epigenetic modifications. In most cases, cytosine (C) in DNA sequence is converted to 5-methylcytosine (5mC) with addition of a methyl group by the enzymatic activity of DNA methyltransferase. DNA methylation plays a role in the regulation of gene expression. It has been reported that abnormal DNA methylation level is involved in many diseases. 5-hydroxymethylcytosine (5hmC), a newly identified epigenetic modification following 5mC, is generated from oxidation of 5mC by the enzymatic activity of TET family proteins. 5hmC may function as a regulator of gene expression as well as 5mC.
Product Type Antibodies Primary
Research Area Epigenetics
Shipping Information 4°C
Size 100 µl
Source / Host rabbit
Storage -20°C
Substrate / Buffer PBS/50% glycerol, pH 7.2
Technical Specifications DNA methylation is one of many critical epigenetic modifications. In most cases, cytosine (C) in DNA sequence is converted to 5-methylcytosine (5mC) with addition of a methyl group by the enzymatic activity of DNA methyltransferase. DNA methylation plays a role in the regulation of gene expression. It has been reported that abnormal DNA methylation level is involved in many diseases. 5-hydroxymethylcytosine (5hmC), a newly identified epigenetic modification following 5mC, is generated from oxidation of 5mC by the enzymatic activity of TET family proteins. 5hmC may function as a regulator of gene expression as well as 5mC.
Product Page Updated 2019-10-21T13:07:42.203Z

Shipping info

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