5-hydroxymethylcytosine (5hmC)
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Specifications
| Country Availability | DK, EE, FI, FO, GL, IS, LT, LV, NO, SE |
| Clone Type | polyclonal |
| Data Sheet Link | https://www.mblintl.com/assets/PM077-v1.pdf |
| Description | Anti-5-hydroxymethylcytosine (5hmC) pAb |
| Supplier | MBL International Corp. |
| Immunogen | BSA-conjugated 5-hydroxymethylcytidine |
| CE/IVD | false |
| Notes | DNA methylation is one of many critical epigenetic modifications. In most cases, cytosine (C) in DNA sequence is converted to 5-methylcytosine (5mC) with addition of a methyl group by the enzymatic activity of DNA methyltransferase. DNA methylation plays a role in the regulation of gene expression. It has been reported that abnormal DNA methylation level is involved in many diseases. 5-hydroxymethylcytosine (5hmC), a newly identified epigenetic modification following 5mC, is generated from oxidation of 5mC by the enzymatic activity of TET family proteins. 5hmC may function as a regulator of gene expression as well as 5mC. |
| Source / Host | rabbit |
| Storage | -20°C |
| Substrate / Buffer | PBS/50% glycerol, pH 7.2 |
| Product Page Updated | 2019-01-15T09:09:13.918Z |
Shipping info
The delivery time for this item is approximately 8-12 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.
