5-hydroxymethylcytosine (5hmC)

Article No PM077
Product Type Antibodies Primary
Research Area Epigenetics
Application IP, WB
Size 100 µl

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Country Availability DK, EE, FI, FO, GL, IS, LT, LV, NO, SE
Clone Type polyclonal
Data Sheet Link https://www.mblintl.com/assets/PM077-v1.pdf
Description Anti-5-hydroxymethylcytosine (5hmC) pAb
Supplier MBL International Corp.
Immunogen BSA-conjugated 5-hydroxymethylcytidine
CE/IVD false
Notes DNA methylation is one of many critical epigenetic modifications. In most cases, cytosine (C) in DNA sequence is converted to 5-methylcytosine (5mC) with addition of a methyl group by the enzymatic activity of DNA methyltransferase. DNA methylation plays a role in the regulation of gene expression. It has been reported that abnormal DNA methylation level is involved in many diseases. 5-hydroxymethylcytosine (5hmC), a newly identified epigenetic modification following 5mC, is generated from oxidation of 5mC by the enzymatic activity of TET family proteins. 5hmC may function as a regulator of gene expression as well as 5mC.
Source / Host rabbit
Storage -20°C
Substrate / Buffer PBS/50% glycerol, pH 7.2
Product Page Updated 2019-01-15T09:09:13.918Z

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rabbit rabbit

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Product data sheet