Article No
PM045
Application | ICC, IHC, IP, WB |
Article No | PM045 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | Anti-p62 (SQSTM1) (Human) pAb |
Supplier | MBL |
Immunogen | Recombinant human p62 (120-440 a.a.) |
Isotype | Ig |
Notes | p62/SQSTM1 interacts with various molecular groups such as RIP, TRAF6, ERK, aPKCs, and poly-ubiquitin through PB1 domain, Zn finger domain, and UBA domain. This protein direct interacts with LC3, which is localized on autophagosome membrane, and is degradated by autophagic-lysosome pathway. p62 regulates ubiquitin-positive protein aggregates caused by autophagy deficiency. |
Product Type | Antibodies Primary |
Research Area | Cell Death |
Shipping Information | 4°C |
Size | 100 µl |
Source / Host | rabbit |
Species Reactivity | human, mouse, rat, hamster, fish |
Stability | 1 year |
Storage | -20°C |
Substrate / Buffer | 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
Technical Specifications | p62/SQSTM1 interacts with various molecular groups such as RIP, TRAF6, ERK, aPKCs, and poly-ubiquitin through PB1 domain, Zn finger domain, and UBA domain. This protein direct interacts with LC3, which is localized on autophagosome membrane, and is degradated by autophagic-lysosome pathway. p62 regulates ubiquitin-positive protein aggregates caused by autophagy deficiency. |
Product Page Updated | 2023-12-29T16:20:16.638Z |