Article No
PAT-QDT4OO-250
Recombinant e.coli mutY protein
Recombinant e.coli mutY protein
Enzymes
Specifications
| MW | 41.5 kDa (373aa) confirmed by MALDI-TOF |
| Accession Number | NP_417436 |
| Application | Electrophoresis |
| Article No | PAT-QDT4OO-250 |
| Biosite Brand | Biosite Proteins |
| Country Availability | all |
| Concentration | 0.25 mg/ml |
| Description | Recombinant e.coli mutY protein |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 947447 |
| Gene Symbol | mutY |
| Notes | Adenine DNA glycosylase, also known as mutY, is an adenine DNA glycosylase active on DNA substrates containing A/G, A/8-oxoG, or A/C mismatches and also has a weak guanine glycosylase activity on G/8-oxoG-containing DNA. mutY is crucial for the avoidance of mutations resulting from oxidative DNA damage. Increasing levels of mutY in A549 cells exposed to oxygen and infrared radiation leads to improvements in cell survival. It is abundant in neurons where mitochondrial genomes exposed to reactive oxygen species (ROS) that damage DNA must maintain integrity over the entire mammalian life span. Recombinant E. coil mutY protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
| Product Type | Enzymes |
| Purity | >90% |
| Sequence | MGSSHHHHHH SSGLVPRGSH MGSMQASQFS AQVLDWYDKY GRKTLPWQID KTPYKVWLSE VMLQQTQVAT VIPYFERFMA RFPTVTDLAN APLDEVLHLW TGLGYYARAR NLHKAAQQVA TLHGGKFPET FEEVAALPGV GRSTAGAILS LSLGKHFPIL DGNVKRVLAR CYAVSGWPGK KEVENKLWSL SEQVTPAVGV ERFNQAMMDL GAMICTRSKP KCSLCPLQNG CIAAANNSWA LYPGKKPKQT LPERTGYFLL LQHEDEVLLA QRPPSGLWGG LYCFPQFADE ESLRQWLAQR QIAADNLTQL TAFRHTFSHF HLDIVPMWLP VSSFTGCMDE GNALWYNLAQ PPSVGLAAPV ERLLQQLRTG APV |
| Size | 250ug |
| Species Reactivity | bacteria |
| Storage | 4°C, -80°C |
| UniProt Number | P17802 |
| Product Page Updated | 2024-04-17T08:28:29.021Z |