Article No
PAT-OI2BQT-250
Recombinant human CD117/c-kit protein
Recombinant human CD117/c-kit protein
Proteins & Peptides
Specifications
| MW | 57.1 kDa (507aa) |
| NCBI Number | NP_000213 |
| Accession Number | NP_000213.1 |
| Application | Electrophoresis |
| Article No | PAT-OI2BQT-250 |
| Biosite Brand | Biosite Proteins |
| Country Availability | all |
| Concentration | 0.25 mg/ml |
| Description | Recombinant human CD117/c-kit protein |
| Supplier | Nordic Biosite |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Entrez Gene ID | 3815 |
| Gene Symbol | KIT |
| Notes | KIT, also known as mast/stem cell growth factor receptor Kit isoform 1, is a cytokine receptor that is expressed not only in hematopoietic stem cells but also in other cell types. It binds to receptor tyrosine kinase type III, a stem cell factor, also called a rigid factor or c-kit ligand. When this receptor binds to stem cell factor (SCF), it forms a dimer that activates intrinsic tyrosine kinase activity, which, in turn, phosphorylates and activates signaling molecules that propagate signals in cells. This receptor protects vascular smooth muscle cells from apoptosis and helps restore cardiac function after myocardial infarction. Recombinant human KIT, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Alias Names | Mast/stem cell growth factor receptor Kit isoform 1, KIT, C-Kit, CD117, PBT, SCFR |
| Previous Article No | PAT-BAE8D0 |
| Product Type | Proteins & Peptides |
| Purity | >90% |
| Sequence | QPSVSPGEPS PPSIHPGKSD LIVRVGDEIR LLCTDPGFVK WTFEILDETN ENKQNEWITE KAEATNTGKY TCTNKHGLSN SIYVFVRDPA KLFLVDRSLY GKEDNDTLVR CPLTDPEVTN YSLKGCQGKP LPKDLRFIPD PKAGIMIKSV KRAYHRLCLH CSVDQEGKSV LSEKFILKVR PAFKAVPVVS VSKASYLLRE GEEFTVTCTI KDVSSSVYST WKRENSQTKL QEKYNSWHHG DFNYERQATL TISSARVNDS GVFMCYANNT FGSANVTTTL EVVDKGFINI FPMINTTVFV NDGENVDLIV EYEAFPKPEH QQWIYMNRTF TDKWEDYPKS ENESNIRYVS ELHLTRLKGT EGGTYTFLVS NSDVNAAIAF NVYVNTKPEI LTYDRLVNGM LQCVAAGFPE PTIDWYFCPG TEQRCSASVL PVDVQTLNSS GPPFGKLVVQ SSIDSSAFKH NGTVECKAYN DVGKTSAYFN FAFKGNNKEQ IHPHTLFTP |
| Size | 250ug |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| Substrate / Buffer | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| UniProt Number | P10721 |
| Product Page Updated | 2024-04-17T08:28:29.021Z |