14-3-3 eta

Article No PAT-83552-2
Product Type Proteins & Peptides
Research Area Cell Signaling
Application Electrophoresis
Size 0.5mg

Specifications

MW 28.2kDa (246aa)
NCBI Number NP_003396
Country Availability all
BioSite Brand BioSite
Concentration 1mg/ml (determined by Absorbance at 280nm)
Description 14-3-3 eta, 1-246aa, Human, E.coli
Supplier BioSite
Notes 14-3-3 eta also as known as YWHAH. This protein belong to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 eta interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function. It implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binding to a large number of partners, usually by recognition of a phosphothreonine motif. Recombinant Human 14-3-3 eta was expressed in E.coli and purified by using conventional chromatography techniques.
Alias Names YWHAH, YWHA1
Purity > 90% by SDS - PAGE
Sequence MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN
Source / Host bacteria
Species Reactivity human
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Substrate / Buffer Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.

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Source/Host:

bacteria

Species reactivity:

human human