Article No
PAT-83552-1
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Proteins & Peptides
14-3-3 eta
14-3-3 eta also as known as YWHAH. This protein belong to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 eta interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function. It implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binding to a large number of partners, usually by recognition of a phosphothreonine motif. Recombinant Human 14-3-3 eta was expressed in E. coli and purified by using conventional chromatography techniques.
Specifications
| MW | 28.2kDa (246aa) |
| NCBI Number | NP_003396 |
| Application | Electrophoresis |
| Article No | PAT-83552-1 |
| BioSite Brand | BioSite |
| Concentration | 1mg/ml (determined by Absorbance at 280nm) |
| Description | 14-3-3 eta also as known as YWHAH. This protein belong to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 eta interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function. It implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binding to a large number of partners, usually by recognition of a phosphothreonine motif. Recombinant Human 14-3-3 eta was expressed in E. coli and purified by using conventional chromatography techniques. |
| Supplier | BioSite |
| Domain | 1-246aa |
| Keywords | Signal Transduction,Transportation,Metabolism |
| Notes | 14-3-3 eta also as known as YWHAH. This protein belong to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 eta interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function. It implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binding to a large number of partners, usually by recognition of a phosphothreonine motif. Recombinant Human 14-3-3 eta was expressed in E.coli and purified by using conventional chromatography techniques. |
| Alias Names | YWHAH, YWHA1 |
| Product Type | Proteins & Peptides |
| Purity | > 90% by SDS - PAGE |
| Research Area | Cell Signaling, Cell Signaling, Metabolism |
| Sequence | MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN |
| Size | 100ug |
| Source / Host | bacteria |
| Species Reactivity | human |
| Storage | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Substrate / Buffer | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| UniProt Number | Q04917 |
| Product Page Updated | 2019-04-15T12:57:56.440Z |
Shipping info
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