Article No
PAT-OR7M2G-100
MW | 27.1 kDa (260aa) confirmed by MALDI-TOF |
NCBI Number | NP_057667 |
Accession Number | NP_057667 |
Application | Electrophoresis |
Article No | PAT-OR7M2G-100 |
Biosite Brand | Biosite Proteins |
Country Availability | all |
Concentration | 0.5 mg/ml |
Description | Recombinant human PLUNC protein |
Supplier | Nordic Biosite |
Entrez Gene ID | 51297 |
Gene Symbol | BPIFA1 |
Notes | BPIFA1, also known as PLuNC, belongs to the short subfamily of PLuNC family proteins and have homology only to the Nterminal domains of BPI. It is a secreted protein that is expressed in the secretory ducts and submucosal glands of tracheobronchial tissues. BPIFA1 binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of BPIFA1 occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals, indicating that long-term exposure to airway irritants impairs the production of BPIFA1 in the upper respiratory tract. Recombinant human BPIFA1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
Alias Names | BPI fold-containing family A member 1, BPI fold-containing family A, member 1, bA49G10.5, LPLuNC3, LuNX, NASG, PLuNC, SPuRT |
Previous Article No | PAT-81908-1 |
Product Type | Proteins & Peptides |
Purity | >90% |
Sequence | MGSSHHHHHH SSGLVPRGSH MGSQFGGLPV PLDQTLPLNV NPALPLSPTG LAGSLTNALS NGLLSGGLLG ILENLPLLDI LKPGGGTSGG LLGGLLGKVT SVIPGLNNII DIKVTDPQLL ELGLVQSPDG HRLYVTIPLG IKLQVNTPLV GASLLRLAVK LDITAEILAV RDKQERIHLV LGDCTHSPGS LQISLLDGLG PLPIQGLLDS LTGILNKVLP ELVQGNVCPL VNEVLRGLDI TLVHDIVNML IHGLQFVIKV |
Size | 100ug |
Species Reactivity | human |
Storage | 4°C, -80°C |
Substrate / Buffer | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol |
UniProt Number | Q9NP55 |
Product Page Updated | 2024-04-17T08:28:29.021Z |