Article No
PAT-YIULYA-250
Recombinant human CARD18 protein
Recombinant human CARD18 protein
Proteins & Peptides
Specifications
| MW | 12.3 kDa (110aa) confirmed by MALDI-TOF |
| NCBI Number | NP_067546 |
| Accession Number | NP_067546 |
| Application | Electrophoresis |
| Article No | PAT-YIULYA-250 |
| Biosite Brand | Biosite Proteins |
| Country Availability | all |
| Concentration | 0.5 mg/ml |
| Description | Recombinant human CARD18 protein |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 59082 |
| Gene Symbol | CARD18 |
| Notes | Caspase recruitment domain-containing protein 18, also known as CARD18, is a member of the death-domain-fold superfamily that is induced by proinflammatory stimuli. It consists essentially only of a CARD, inhibits generation of IL-1b by interacting with caspase-1 and preventing association with RIP 2. The association of CARD18 with caspase-1 is facilitated by the charge-charge interactions between the prodomain of caspase-1 and the surface charge of CARD18. Recombinant human CARD18 proetin, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
| Alias Names | Caspase recruitment domain-containing protein 18, ICEBERG, pseudo-ICE, uNQ5804 |
| Previous Article No | PAT-81500-1 |
| Product Type | Proteins & Peptides |
| Purity | >95% |
| Sequence | MGSSHHHHHH SSGLVPRGSH MADQLLRKKR RIFIHSVGAG TINALLDCLL EDEVISQEDM NKVRDENDTV MDKARVLIDL VTGKGPKSCC KFIKHLCEED PQLASKMGLH |
| Size | 250ug |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| Substrate / Buffer | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,10% glycerol, 0.1M NaCl |
| UniProt Number | P57730 |
| Product Page Updated | 2024-04-17T08:28:29.021Z |