Article No
PAT-0SQ0FO-50
Recombinant rat TIMP-1 protein
Recombinant rat TIMP-1 protein
Enzymes
Specifications
| MW | 22.3 kDa (200aa) |
| NCBI Number | NP_446271 |
| Accession Number | NP_446271 |
| Application | Electrophoresis |
| Article No | PAT-0SQ0FO-50 |
| Biosite Brand | Biosite Proteins |
| Country Availability | all |
| Concentration | 0.5 mg/ml |
| Description | Recombinant rat TIMP-1 protein |
| Supplier | Nordic Biosite |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Entrez Gene ID | 116510 |
| Gene Symbol | Timp1 |
| Notes | TIMP1, also known as metalloproteinase inhibitor 1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. MMP1 functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. It plays a role in integrin signaling. Recombinant rat TIMP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Alias Names | Timp1, Timp, TIMP-1 |
| Previous Article No | 209-0SQ0FO-50, PAT-0SQ0FO-50 |
| Product Type | Enzymes |
| Purity | >90% |
| Sequence | CSCAPTHPQT AFCNSDLVIR AKFMGSPEII ETTLYQRYEI KMTKMLKGFD AVGNATGFRF AYTPAMESLC GYVHKSQNRS EEFLIAGRLR NGNLHITACS FLVPWHNLSP AQQKAFVKTY SAGCGVCTVF PCSAIPCKLE SDSHCLWTDQ ILMGSEKGYQ SDHFACLPRN PDLCTWQYLG VSMTRSLPLA KAEA |
| Size | 50ug |
| Species Reactivity | rat |
| Storage | 4°C, -80°C |
| Substrate / Buffer | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| UniProt Number | P30120 |
| Product Page Updated | 2024-04-17T08:28:29.021Z |