Article No
P009-5MG
Specifications
| CAS No | 10083-24-6 |
| Article No | P009-5MG |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Components | Inhibitor / activator |
| Description | Piceatannol |
| Supplier | Arbor Assays |
| Notes | Activator of human deacetylase SIRT1. Anti-inflammatory, immunomodulatory and antiproliferative agent that inhibits p56lck and syk protein tyrosine kinases and inhibits TNF-induced NF-kB activation and gene expression. Piceatannol is a resveratrol analog formed by the cytochrome P450-catalyzed hydroxylation of resveratrol. Piceatannol exhibits potent anticancer properties by inducing apoptosis in BJAB Burkitt-like lymphoma cells with an ED50 value of 25 µM. Piceatannol also exhibits anti-proliferative and anti-inflammatory effects by inhibiting the activity of a wide range of tyrosine and serine/threonine protein kinases and suppressing NF-kB activation through inhibition of IkBa kinase. |
| Product Type | Chemicals & Biochemicals |
| Research area | Molecular Biology |
| Shipping Information | BLUE ICE |
| Size | 5MG |
| Species Reactivity | synthetic |
| Storage | RT |
| Product Page Updated | 2024-03-04T10:32:24.675Z |
