Antibodies Primary

KDM3A Antibody

NEW
KDM3A Antibody
This item can unfortunately not be purchased via our website. Please send an email to info@nordicbiosite.com, and we will handle your order directly.

Article No

OAEC04709

Application

WB, IF, ELISA

Species Reactivity

human

Size

100 ug/100 ul

Clone

20

Source / Host

mouse

Shipping Information

Wet Ice

Product insert

Specifications

MW 147 kDa
Additional Information This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. JMJD1A functions as a mono- anddimethylation-specific demethylase, binding iron and -ketoglutarate as cofactors anddemethylating Lys ine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the expression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin) and, therefore, plays an essential role in spermatogenesis.
Application WB, IF, ELISA
Article No OAEC04709
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL
Clone 20
Clone Type monoclonal
Description KDM3A Antibody
Supplier Aviva Systems Biology
Immunogen Purified recombinant fragment of human KDM3A expres sed in E. Coli.
Isotype IgG1
Keywords Monoclonal;
Notes This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. JMJD1A functions as a mono- anddimethylation-specific demethylase, binding iron and -ketoglutarate as cofactors anddemethylating Lys ine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the expression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin) and, therefore, plays an essential role in spermatogenesis.
Alias Names TSGA, JMJD1, JHDM2A, JHMD2A, JMJD1A
Product Type Antibodies Primary
Shipping Information Wet Ice
Size 100 ug/100 ul
Source / Host mouse
Species Reactivity human
Storage Store at 4C, for long term storage, store at -20C.
Substrate / Buffer Ascitic fluid containing 0.03% sodium azide
Technical Specifications <b style='color:#DC6809'>Click <a href='//www.avivasysbio.com/sd/category/conjugation/conjugation.phtml' target='_blank'>here</a> to learn more about Aviva's By-Request Conjugation Service.</b>
Product Page Updated 2019-10-21T12:16:03.719Z

Shipping info

The delivery time for this item is approximately 8-16 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.