Article No
MON9813
Mouse anti-Adiponectin, clone A-492
Mouse anti-Adiponectin, clone A-492
Antibodies Primary
Specifications
| Additional Information | A-492 reacts with adiponectin, an adipocytokin; adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has an insulin like effect on glucose levels in the blood. Plasma adiponectin levels are found in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. |
| Application | ELISA |
| Article No | MON9813 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | A-492 |
| Clone Type | monoclonal |
| Concentration | 100 ug/ml |
| Conjugation | Unconjugated |
| Description | Mouse anti-Adiponectin, clone A-492 |
| Supplier | SANBIO bv/Monosan |
| Format | - |
| Immunogen | adiponectin |
| Isotype | IgG1 k |
| Notes | A-492 reacts with adiponectin, an adipocytokin; adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has an insulin like effect on glucose levels in the blood. Plasma adiponectin levels are found in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. |
| Product Type | Antibodies Primary |
| Protocol | ELISA, IHC-fr, IHC-P |
| Shipping Information | blue ice |
| Size | 100 ug |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 2-8°C |
| Substrate / Buffer | PBS with 0.02% sodium azide |
| Product Page Updated | 2024-01-12T18:37:31.725Z |
