Article No
MON5073
Rat anti-Mouse IL-6, clone MP5-20F3
Rat anti-Mouse IL-6, clone MP5-20F3
Antibodies Primary
Specifications
| Additional Information | The antibody neutralizes mouse interleukin 6 (IL-6). It does not cross-react with LPS (the component of the bacterial cell wall which is considered responsible for the toxicity of gram-negative bacteria) and TNFalpha nor does it bind to either human or rat IL-6. The antibody inhibits IL-6 induced proliferation of the B9 assay. IL-6 is a pluripotent 20-22 kDa cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and haematopoiesis. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas. |
| Application | ELISA, IP |
| Article No | MON5073 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | MP5-20F3 |
| Clone Type | monoclonal |
| Concentration | 100 ug/ml |
| Conjugation | Unconjugated |
| Description | Rat anti-Mouse IL-6, clone MP5-20F3 |
| Supplier | SANBIO bv/Monosan |
| Format | - |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG1 |
| Notes | The antibody neutralizes mouse interleukin 6 (IL-6). It does not cross-react with LPS (the component of the bacterial cell wall which is considered responsible for the toxicity of gram-negative bacteria) and TNFalpha nor does it bind to either human or rat IL-6. The antibody inhibits IL-6 induced proliferation of the B9 assay. IL-6 is a pluripotent 20-22 kDa cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and haematopoiesis. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas. |
| Product Type | Antibodies Primary |
| Protocol | FUNC, ELISA, IP |
| Shipping Information | blue ice |
| Size | 1 ml |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 2-8°C |
| Substrate / Buffer | PBS with 0.1% BSA and 0.02% sodium azide |
| Product Page Updated | 2024-01-12T18:37:31.725Z |
