Article No
MON3326
Mouse anti-Human p27, clone SX53G8
Mouse anti-Human p27, clone SX53G8
Antibodies Primary
Specifications
| Additional Information | p27, also known as cyclin-dependent kinase inhibitor 1B (CDNK1B), is a kinase inhibitor that controls cell cycle progression.1-4 p27 is involved in G1 phase arrest and obstructs cell entry into the S phase by binding to and inhibiting cyclin E-CDK2, effectively slowing or stopping the cell division cycle.1-4 p27 is broadly expressed in normal tissue but can be dysfunctional in neoplastic tissue and, therefore, not expressed. |
| Application | IHC |
| Article No | MON3326 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | SX53G8 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Mouse anti-Human p27, clone SX53G8 |
| Supplier | SANBIO bv/Monosan |
| Format | - |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG1 k |
| Notes | p27, also known as cyclin-dependent kinase inhibitor 1B (CDNK1B), is a kinase inhibitor that controls cell cycle progression.1-4 p27 is involved in G1 phase arrest and obstructs cell entry into the S phase by binding to and inhibiting cyclin E-CDK2, effectively slowing or stopping the cell division cycle.1-4 p27 is broadly expressed in normal tissue but can be dysfunctional in neoplastic tissue and, therefore, not expressed. |
| Product Type | Antibodies Primary |
| Protocol | IHC-P (1:100-1:500) |
| Shipping Information | blue ice |
| Size | 1 ml |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 2-8°C |
| Substrate / Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Product Page Updated | 2024-01-12T18:37:31.725Z |
