Article No
M153-3
Application | WB |
Article No | M153-3 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 4D3 |
Clone Type | monoclonal |
Concentration | 1 mg/mL |
Conjugation | Unconjugated |
Description | Anti-Atg5 |
Supplier | MBL |
Immunogen | Full-length recombinant human Atg5 (275 a.a.) |
Isotype | IgG1 k |
Notes | Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Autophagy has two ubiquitin-like conjugation systems, the Atg12 and LC3-II systems. In the Atg12 conjugation system, the Atg12-Atg5-Atg16L forms 800 kDa complex that elongates autophagic isolation membrane. After completion of the formation of the autophagosome, the Atg12-Atg5-Atg16L complex dissociates from the membrane. |
Product Type | Antibodies Primary |
Research Area | Cell Death |
Shipping Information | 4°C |
Size | 100 µg |
Source / Host | mouse |
Species Reactivity | human, mouse, hamster |
Stability | 1 year |
Storage | -20°C |
Substrate / Buffer | 100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
Technical Specifications | Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Autophagy has two ubiquitin-like conjugation systems, the Atg12 and LC3-II systems. In the Atg12 conjugation system, the Atg12-Atg5-Atg16L forms 800 kDa complex that elongates autophagic isolation membrane. After completion of the formation of the autophagosome, the Atg12-Atg5-Atg16L complex dissociates from the membrane. |
Product Page Updated | 2023-12-29T16:20:16.638Z |