Apolipoprotein E (ApoE), a 35 kDa plasma protein containing sialic acid, plays a role in triglyceride, cholesterol transport and metabolism, and known to be synthesized in liver, brain and other organs. ApoE is a polymorphic apolipoprotein exhibiting three isoforms such as Apo E2, E3 and E4 coded for by three alleles of ε2, ε3 and ε4 at a single gene locus respectively.
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