Article No
LS-G145907-100
Coronavirus SARS-CoV-2 S1 Protein (Recombinant Fc, C-terminus) (Val16-Arg685)
SARS-CoV-2 S1 Protein LS-G145907 is a Recombinant Coronavirus SARS-CoV-2 S1 produced in HEK 293 Cells Val16-Arg685 with Fc, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method).
Proteins & Peptides
Specifications
| Article No | LS-G145907-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Description | SARS-CoV-2 S1 Protein LS-G145907 is a Recombinant Coronavirus SARS-CoV-2 S1 produced in HEK 293 Cells Val16-Arg685 with Fc, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). |
| Supplier | LifeSpan Biosciences |
| Notes | Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
| Product Type | Proteins & Peptides |
| Purity | >85% |
| Shipping Information | BLUE ICE |
| Size | 100 µg |
| Storage | -20°C, 4°C, -80°C |
| Technical Specifications | SARS-CoV-2 S1 Protein LS-G145907 is a Recombinant Coronavirus SARS-CoV-2 S1 produced in HEK 293 Cells Val16-Arg685 with Fc, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). |
| Product Page Updated | 2024-04-12T12:29:59.363Z |