Article No
LS-C744231-5
Application | IHC |
Article No | LS-C744231-5 |
Country Availability | SE, FI, DK, NO, FO, GL |
Clone | HMB45 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | HMB45 antibody LS-C744231 is an unconjugated mouse monoclonal antibody to human HMB45. Validated for IHC. |
Supplier | LifeSpan Biosciences |
Immunogen | Extract from lymph node metastases of melanoma |
Isotype | IgG1 |
Notes | HMB45 antibody LS-C744231 is an unconjugated mouse monoclonal antibody to human HMB45. Validated for IHC. |
Alias Names | , |
Product Type | Antibodies Primary |
Protocol | Pre-treatment with pronase 0.1% or antigen retrieval The antibody HMB45 is used for the discrimination of Melanoma from normal Melanocytes. Melanoic Schwannoma Clear Cell Sarcoma will also be stained. Negative are tumours of epithelial, lymphoid, glial and mesenchymal origin. Melanocytes are pigmented, melanin containing cells being located mainly in the epidermis. They protect tissues from UVB irradiation of the sun. The antibody HMB45 reacts with fetal and neonatal Melanocytes, with junctional and blue naevus cells, but not with intradermal naevi and adult melanocytes. Neuraminidase-sensitive glycoconjugate on the surface of human melanosomes. |
Shipping Information | RT |
Size | 5 ml |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
Substrate / Buffer | PBS, pH 7.3, 0.09% Sodium Azide |
Technical Specifications | Pre-treatment with pronase 0.1% or antigen retrieval The antibody HMB45 is used for the discrimination of Melanoma from normal Melanocytes. Melanoic Schwannoma Clear Cell Sarcoma will also be stained. Negative are tumours of epithelial, lymphoid, glial and mesenchymal origin. Melanocytes are pigmented, melanin containing cells being located mainly in the epidermis. They protect tissues from UVB irradiation of the sun. The antibody HMB45 reacts with fetal and neonatal Melanocytes, with junctional and blue naevus cells, but not with intradermal naevi and adult melanocytes. Neuraminidase-sensitive glycoconjugate on the surface of human melanosomes. |
Product Page Updated | 2024-04-12T11:52:25.099Z |
Volume | 5 ml |