Article No
LS-C57975-100
CD80
CD80 antibody LS-C57975 is an RPE-conjugated rat monoclonal antibody to mouse CD80. Validated for Flow.
Antibodies Primary
Specifications
| NCBI Number | 941 |
| Application | FC |
| Article No | LS-C57975-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | RM80 |
| Clone Type | monoclonal |
| Conjugation | PE |
| Description | CD80 antibody LS-C57975 is an RPE-conjugated rat monoclonal antibody to mouse CD80. Validated for Flow. |
| Recommended Dilution | FC (1:1) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 941 |
| Gene Symbol | CD80 |
| Immunogen | BCL1 cells expressing CD80 |
| Isotype | IgG2a |
| Notes | CD80 antibody LS-C57975 is an RPE-conjugated rat monoclonal antibody to mouse CD80. Validated for Flow. |
| Alias Names | CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 molecule, CTLA-4 counter-receptor B7.1 |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. |
| Purification | Affinity Purified |
| Shipping Information | RT |
| Size | 100 tst |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 4°C |
| Substrate / Buffer | PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA |
| Technical Specifications | Recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses. |
| Product Page Updated | 2024-04-12T09:51:03.289Z |
| Volume | 100 tst |
