Article No
LS-C391562-20
MAGEA1 / MAGE 1
MAGE 1 antibody LS-C391562 is an unconjugated mouse monoclonal antibody to MAGE 1 (MAGEA1) from human. It is reactive with human, rat and dog. Validated for Flow, IF, IHC and WB.
Antibodies Primary
Specifications
| NCBI Number | 4100 |
| Application | FC, IF, IHC, WB |
| Article No | LS-C391562-20 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | MA454 |
| Clone Type | monoclonal |
| Concentration | 0.2 mg/ml |
| Conjugation | Unconjugated |
| Description | MAGE 1 antibody LS-C391562 is an unconjugated mouse monoclonal antibody to MAGE 1 (MAGEA1) from human. It is reactive with human, rat and dog. Validated for Flow, IF, IHC and WB. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (1 - 2 ug/ml), IHC-P (0.5 - 1 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 4100 |
| Gene Symbol | MAGEA1 |
| Immunogen | Full length human protein. |
| Isotype | IgG1 k |
| Notes | MAGE 1 antibody LS-C391562 is an unconjugated mouse monoclonal antibody to MAGE 1 (MAGEA1) from human. It is reactive with human, rat and dog. Validated for Flow, IF, IHC and WB. |
| Alias Names | MAGEA1, Antigen MZ2-E, Cancer/testis antigen 1.1, CT1.1, MAGE-1 antigen, MAGE1A, Melanoma antigen family A 1, Melanoma antigen MAGE-1, MAGE 1, MAGE1, Melanoma-associated antigen 1 |
| Product Type | Antibodies Primary |
| Protocol | Recognizes a protein of 42-46kDa, identified as MAGE-1. This mAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy. The optimal dilution of the MAGE-1 antibody for each application should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 20 µg |
| Source / Host | mouse |
| Species Reactivity | dog/canine, human, rat |
| Storage | 4°C |
| Substrate / Buffer | PBS, pH 7.4, 0.1mg/ml BSA, 0.05% sodium azide |
| Technical Specifications | Human MAGEA1 / MAGE 1 |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
