Article No
LS-C391117-7
NCBI Number | 7412 |
Application | FC, IF, IHC |
Article No | LS-C391117-7 |
Country Availability | SE, FI, DK, NO, FO, GL |
Clone | 1.4C3 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | CD106 antibody LS-C391117 is an unconjugated mouse monoclonal antibody to human CD106 (VCAM1). Validated for Flow, IF and IHC. |
Recommended Dilution | IHC-P (1:1) |
Supplier | LifeSpan Biosciences |
Entrez Gene ID | 7412 |
Gene Symbol | VCAM1 |
Immunogen | Stimulated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM-1 antibody. |
Isotype | IgG1 k |
Notes | CD106 antibody LS-C391117 is an unconjugated mouse monoclonal antibody to human CD106 (VCAM1). Validated for Flow, IF and IHC. |
Alias Names | VCAM1, CD106, CD106 antigen, INCAM-100, V-CAM 1, VCAM-1 |
Product Type | Antibodies Primary |
Protocol | The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. VCAM-1 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. Optimal dilution of the VCAM-1 antibody should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. |
Purification | Protein G Purified |
Shipping Information | RT |
Size | 7 ml |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
Substrate / Buffer | PBS, 0.01% BSA, 0.05% sodium azide |
Technical Specifications | Human VCAM1 / CD106 |
Product Page Updated | 2024-03-11T11:55:05.043Z |
Volume | 7 ml |