Article No
LS-C390359-100
TNC / Tenascin C
Tenascin C antibody LS-C390359 is an unconjugated mouse monoclonal antibody to human Tenascin C (TNC). Validated for Flow, IF and IHC.
Antibodies Primary
Specifications
| NCBI Number | 3371 |
| Application | FC, IF, IHC |
| Article No | LS-C390359-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | T2H5 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Tenascin C antibody LS-C390359 is an unconjugated mouse monoclonal antibody to human Tenascin C (TNC). Validated for Flow, IF and IHC. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (0.5 - 1 ug/ml), IHC-P (2 - 4 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 3371 |
| Gene Symbol | TNC |
| Immunogen | Human breast carcinoma cells were used as the immunogen for the Tenascin C antibody. |
| Isotype | IgG1 k |
| Notes | Tenascin C antibody LS-C390359 is an unconjugated mouse monoclonal antibody to human Tenascin C (TNC). Validated for Flow, IF and IHC. |
| Alias Names | TNC, 150-225, Cytotactin, GP, Hexabrachion (tenascin), GMEM, GP 150-225, Miotendinous antigen, Myotendinous antigen, JI, Tenascin, Tenascin C, Neuronectin, Tenascin-C isoform 14/AD1/16, TN-C, Hexabrachion, HXB, Tenascin-C, TN |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this mAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linked hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas. Optimal dilution of the Tenascin C antibody should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| Substrate / Buffer | Sterile Solution PBS |
| Technical Specifications | Human TNC / Tenascin C |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
