Article No
LS-C390057-100
CD55
CD55 antibody LS-C390057 is an unconjugated mouse monoclonal antibody to human CD55. Validated for Flow, IF and IHC.
Antibodies Primary
Specifications
| NCBI Number | 1604 |
| Application | FC, IF, IHC |
| Article No | LS-C390057-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | 143-30 |
| Clone Type | monoclonal |
| Concentration | 0.2 mg/ml |
| Conjugation | Unconjugated |
| Description | CD55 antibody LS-C390057 is an unconjugated mouse monoclonal antibody to human CD55. Validated for Flow, IF and IHC. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (0.5 - 1 ug/ml), IHC-Fr (0.5 - 1 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 1604 |
| Gene Symbol | CD55 |
| Immunogen | PHA stimulated human PBL were used as the immunogen for the CD55 antibody. |
| Isotype | IgG1 k |
| Notes | CD55 antibody LS-C390057 is an unconjugated mouse monoclonal antibody to human CD55. Validated for Flow, IF and IHC. |
| Alias Names | CD55, CD55 antigen, Decay-accelerating factor, TC, CR, CROM, DAF |
| Product Type | Antibodies Primary |
| Protocol | Recognizes a single chain glycoprotein of 70kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The mAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH). Optimal dilution of the CD55 antibody should be determined by the researcher. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| Substrate / Buffer | 0.01% BSA, 0.05% sodium azide |
| Technical Specifications | Human CD55 |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
