Article No
LS-C389669-100
ACTH
ACTH antibody LS-C389669 is an unconjugated mouse monoclonal antibody to ACTH (aa1-24) from human. It is reactive with human, mouse and rat. Validated for ELISA, Flow, IF, IHC, IP and WB.
Antibodies Primary
Specifications
| Application | ELISA, FC, IF, IHC, IP, WB |
| Article No | LS-C389669-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | 2F6 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | ACTH antibody LS-C389669 is an unconjugated mouse monoclonal antibody to ACTH (aa1-24) from human. It is reactive with human, mouse and rat. Validated for ELISA, Flow, IF, IHC, IP and WB. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (0.5 - 1 ug/ml), IHC-P (0.5 - 1 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Immunogen | A synthetic peptide corresponding to aa 1-24 of human ACTH. |
| Isotype | IgG1 k |
| Notes | ACTH antibody LS-C389669 is an unconjugated mouse monoclonal antibody to ACTH (aa1-24) from human. It is reactive with human, mouse and rat. Validated for ELISA, Flow, IF, IHC, IP and WB. |
| Alias Names | , ACTH |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific post-translational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH (also called Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This antibody is specific to Synacthen (aa 1-24 of ACTH) and does not react with CLIP (aa 17-39 of ACTH). ACTH is produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. ACTH antibody is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH. ELISA: Order BSA-free format for coating. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat |
| Storage | 4°C |
| Substrate / Buffer | Sterile Solution PBS |
| Technical Specifications | Human ACTH |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
