Article No
LS-C389526-100
CCND1 / Cyclin D1
Cyclin D1 antibody LS-C389526 is an unconjugated mouse monoclonal antibody to Cyclin D1 (CCND1) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF, IHC and WB.
Antibodies Primary
Specifications
| NCBI Number | 595 |
| Application | FC, IF, IHC, WB |
| Article No | LS-C389526-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | DCS-6 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Cyclin D1 antibody LS-C389526 is an unconjugated mouse monoclonal antibody to Cyclin D1 (CCND1) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF, IHC and WB. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (1 - 2 ug/ml), IHC-P (0.5 - 1 ug/ml), WB (0.5 - 1 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 595 |
| Gene Symbol | CCND1 |
| Immunogen | Human recombinant full length protein. |
| Isotype | IgG2a k |
| Notes | Cyclin D1 antibody LS-C389526 is an unconjugated mouse monoclonal antibody to Cyclin D1 (CCND1) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF, IHC and WB. |
| Alias Names | CCND1, B-cell lymphoma 1 protein, BCL-1 oncogene, B-cell CLL/lymphoma 1, BCL-1, Cyclin D1, G1/S-specific cyclin-D1, U21B31, PRAD1, BCL1, D11S287E, PRAD1 oncogene |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody recognizes a protein of 36kDa, identified as Cyclin D1. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms and a key cell cycle regulator. This antibody neutralizes the activity of Cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t (11. 14) (q13. q32) translocation resulting in over-expression. Cyclin D1 antibody is useful in identifying mantle cell lymphomas, which stain positive, from CLL/SLL and follicular lymphomas, which stain negative. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1. ELISA: Order BSA and Azide-free format for coating. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human, monkey, mouse, rat |
| Storage | 4°C |
| Substrate / Buffer | Sterile Solution PBS |
| Technical Specifications | Human CCND1 / Cyclin D1 |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
