Article No
LS-C389520-100
CDKN1A / WAF1 / p21
P21 antibody LS-C389520 is an unconjugated mouse monoclonal antibody to p21 (CDKN1A / WAF1) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF and IHC.
Antibodies Primary
Specifications
| NCBI Number | 1026 |
| Application | FC, IF, IHC |
| Article No | LS-C389520-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | WA-1 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | P21 antibody LS-C389520 is an unconjugated mouse monoclonal antibody to p21 (CDKN1A / WAF1) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF and IHC. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (1 - 2 ug/ml), IHC-P (0.5 - 1 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 1026 |
| Gene Symbol | CDKN1A |
| Immunogen | Human recombinant protein. |
| Isotype | IgG1 k |
| Notes | P21 antibody LS-C389520 is an unconjugated mouse monoclonal antibody to p21 (CDKN1A / WAF1) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF and IHC. |
| Alias Names | CDKN1A, CDKN1, CIP1, CDK-interacting protein 1, DNA synthesis inhibitor, p21CIP1, MDA6, PIC1, SDI1, WAF1, CAP20, CDK-interaction protein 1, MDA-6, p21 |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody recognizes a 21kDa protein, identified as the p21 or p21WAF1 tumor suppressor protein. This antibody is highly specific and shows no cross-reaction with other closely related mitotic inhibitors. p21 is a specific inhibitor of cdk's and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. p21 expression is induced by the wild type, but not mutant, p53. Normal cells generally display a rather intense nuclear expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma). |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human, monkey, mouse, rat |
| Storage | 4°C |
| Substrate / Buffer | Sterile Solution PBS |
| Technical Specifications | Human CDKN1A / WAF1 / p21 |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
