Article No
LS-C388220-20
CD79A / CD79 Alpha
CD79 Alpha antibody LS-C388220 is an unconjugated mouse monoclonal antibody to CD79 Alpha (CD79A) (aa202-216) from human. It is reactive with human, mouse and rat. Validated for Flow, IF and IHC.
Antibodies Primary
Specifications
| NCBI Number | 973 |
| Application | FC, IF, IHC |
| Article No | LS-C388220-20 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | HM47/A9 |
| Clone Type | monoclonal |
| Concentration | 0.2 mg/ml |
| Conjugation | Unconjugated |
| Description | CD79 Alpha antibody LS-C388220 is an unconjugated mouse monoclonal antibody to CD79 Alpha (CD79A) (aa202-216) from human. It is reactive with human, mouse and rat. Validated for Flow, IF and IHC. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (0.5 - 1 ug/ml), IHC-P (0.5 - 1 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 973 |
| Gene Symbol | CD79A |
| Immunogen | Synthetic peptide (GTYQDVGSLNIADVQ, aa202-216) of human CD79a protein. Percent identity by BLAST analysis: Human (93%); Ferret, Cat, Bat, Hamster, Horse, Pig, Guinea pig, Dog (87%); Sheep, Bovine, Elephant (80%); Mouse, Rat (73%). |
| Isotype | IgG1 k |
| Notes | CD79 Alpha antibody LS-C388220 is an unconjugated mouse monoclonal antibody to CD79 Alpha (CD79A) (aa202-216) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF and IHC. |
| Alias Names | CD79A, CD79a antigen, Ig-alpha, MB-1, MB-1 membrane glycoprotein, Surface IgM-associated protein, MB1 |
| Product Type | Antibodies Primary |
| Protocol | CD79a is required in cooperation with CD79b for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells. [UniProt] Staining of FFPE tissues requires boiling sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 20 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat |
| Storage | 4°C |
| Substrate / Buffer | 0.01% BSA, 0.05% sodium azide |
| Technical Specifications | Human CD79A / CD79 Alpha. Human CD79A / CD79 Alpha |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
