Article No
LS-C358075-100
NKX2-1 / Thyroid-Specific TF
Thyroid-Specific TF antibody LS-C358075 is an unconjugated mouse monoclonal antibody to Thyroid-Specific TF (NKX2-1) from rat. It is reactive with human, mouse and rat. Validated for Flow, IF and IHC.
Antibodies Primary
Specifications
| NCBI Number | 7080 |
| Application | FC, IF, IHC |
| Article No | LS-C358075-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | 8G7G3/1 |
| Clone Type | monoclonal |
| Concentration | 0.2 mg/ml |
| Conjugation | Unconjugated |
| Description | Thyroid-Specific TF antibody LS-C358075 is an unconjugated mouse monoclonal antibody to Thyroid-Specific TF (NKX2-1) from rat. It is reactive with human, mouse and rat. Validated for Flow, IF and IHC. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (0.5 - 1 ug/ml), IHC-P (0.5 - 1 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 7080 |
| Gene Symbol | NKX2-1 |
| Immunogen | Rat full length TTF1 / NKX2.1 recombinant protein. |
| Isotype | IgG1 k |
| Notes | Thyroid-Specific TF antibody LS-C358075 is an unconjugated mouse monoclonal antibody to Thyroid-Specific TF (NKX2-1) from rat. It is reactive with human, mouse and rat. Validated for Flow, IF and IHC. |
| Alias Names | NKX2-1, BCH, Benign chorea, Homeobox protein Nkx-2.1, NK-2, NKX2.1, NK-2 homolog A, Thyroid transcription factor 1, NK2 homeobox 1, TTF-1, BHC, Thyroid nuclear factor 1, TITF1, NKX2A, TEBP |
| Product Type | Antibodies Primary |
| Protocol | This mAb recognizes a protein of 40kDa, identified as Thyroid transcription factor 1. TTF1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. antibody to TTF1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. The antibody can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF1 reactivity is also seen in thyroid malignancies. ELISA: Order BSA-free format for coating. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat |
| Storage | 4°C |
| Substrate / Buffer | PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide |
| Technical Specifications | Rat TTF-1 / Thyroid-Specific TF |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
