Article No
LS-C357784-100
CD63
CD63 antibody LS-C357784 is an unconjugated mouse monoclonal antibody to CD63 from human. It is reactive with human and mouse. Validated for ELISA, Flow, IF, IHC, IP and WB.
Antibodies Primary
Specifications
| NCBI Number | 967 |
| Application | ELISA, FC, IF, IHC, IP, WB |
| Article No | LS-C357784-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | NKI/C3 |
| Clone Type | monoclonal |
| Concentration | 0.2 mg/ml |
| Conjugation | Unconjugated |
| Description | CD63 antibody LS-C357784 is an unconjugated mouse monoclonal antibody to CD63 from human. It is reactive with human and mouse. Validated for ELISA, Flow, IF, IHC, IP and WB. |
| Recommended Dilution | FC (0.5 - 1 ug/10e6 cells), IF (0.5 - 1 ug/ml), IHC-P (0.5 - 1 ug/ml), WB (0.5 - 1 ug/ml) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 967 |
| Gene Symbol | CD63 |
| Immunogen | The smooth plasma membrane fraction of MeWo cells. |
| Isotype | IgG1 k |
| Notes | CD63 antibody LS-C357784 is an unconjugated mouse monoclonal antibody to CD63 from human. It is reactive with human and mouse. Validated for ELISA, Flow, IF, IHC, IP and WB. |
| Alias Names | CD63, CD63 molecule, LAMP-3, ME491, Granulophysin, MLA1, Tetraspanin-30, Tspan-30, CD63 antigen, OMA81H, TSPAN30 |
| Product Type | Antibodies Primary |
| Protocol | The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. It is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. Deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression. ELISA: Order BSA-free antibody format for coating. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Storage | 4°C |
| Substrate / Buffer | PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide |
| Technical Specifications | Human CD63 |
| Product Page Updated | 2024-04-12T09:20:06.597Z |
