Article No
LS-C188582-0.1
NCBI Number | 6010 |
Application | IF, IHC, IP, WB |
Article No | LS-C188582-0.1 |
Country Availability | SE, FI, DK, NO, FO, GL |
Clone | 1D4 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | RHO antibody LS-C188582 is an unconjugated mouse monoclonal antibody to bovine RHO (Rhodopsin). Validated for IF, IHC, IP and WB. |
Recommended Dilution | IHC-P (1:100), WB (1:1000) |
Supplier | LifeSpan Biosciences |
Entrez Gene ID | 6010 |
Gene Symbol | RHO |
Immunogen | Bovine rhodopsin. |
Isotype | IgG1 |
Notes | RHO antibody LS-C188582 is an unconjugated mouse monoclonal antibody to bovine RHO (Rhodopsin). Validated for IF, IHC, IP and WB. |
Alias Names | RHO, CSNBAD1, OPN2, Rhodopsin, RP4, Opsin 2, rod pigment, Opsin-2 |
Product Type | Antibodies Primary |
Purification | Protein G Purified |
Shipping Information | RT |
Size | 0.1 ml |
Source / Host | mouse |
Species Reactivity | cow/bovine |
Storage | -20°C |
Substrate / Buffer | 10mM HEPES, pH 7.5, 150mM NaCl, 0.09% Sodium Azide, 50% Glycerol, 0.01% BSA |
Technical Specifications | Recognizes rhodopsin, a pigment of the retina responsible for the formation of photoreceptor cells and the first events in the perception of light. Rhodopsin consists of the protein opsin and a reversibly bound cofactor, retinal, a photoreactive chromophore. Upon light absorption the 11-cis-retinal is isomerized to all-trans retinal, leading to a change in the shape of rhodopsin. The change activates the associated G protein and triggers a second messenger cascade, eventually resulting in the transmission of a nerve impulse to the brain. The trans-retinal is released and converted back into 11-cis-retinal for re-entry into the cycle. Defects in the gene cause various retinopathies such as retinitis pigmentosa and X-linked congenital stationary night blindness. |
Product Page Updated | 2024-04-12T06:35:05.844Z |
Volume | 0.1 ml |