Article No
LS-C188481-0.2
Application | ELISA |
Article No | LS-C188481-0.2 |
Country Availability | SE, FI, DK, NO, FO, GL |
Clone | 5B8 |
Clone Type | monoclonal |
Concentration | 1 mg/ml |
Conjugation | Unconjugated |
Description | Insulin C-Peptide antibody LS-C188481 is an unconjugated mouse monoclonal antibody to human Insulin C-Peptide. Validated for ELISA. |
Supplier | LifeSpan Biosciences |
Immunogen | Recombinant C-peptide. |
Isotype | IgG1 |
Notes | Insulin C-Peptide antibody LS-C188481 is an unconjugated mouse monoclonal antibody to human Insulin C-Peptide. Validated for ELISA. |
Product Type | Antibodies Primary |
Purification | Protein A Purified |
Shipping Information | RT |
Size | 0.2 mg |
Source / Host | mouse |
Species Reactivity | human |
Storage | -20°C |
Substrate / Buffer | PBS, 0.09% Sodium Azide |
Technical Specifications | Recognizes human C-peptide. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+ -ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Levels of C-peptide can be used to distinguish between type 1 and type 2 diabetes. Patients with type 1 diabetes will usually have decreased levels of C-peptide, while patients with type 2 diabetes will have normal or higher than normal levels. The antibody does not cross-react with human, bovine, porcine, mouse or rat insulin. |
Product Page Updated | 2024-03-11T11:14:48.881Z |