Article No
LS-C188425-100
CD86
CD86 antibody LS-C188425 is an RPE-conjugated mouse monoclonal antibody to rat CD86. Validated for Flow.
Antibodies Primary
Specifications
| NCBI Number | 942 |
| Application | FC |
| Article No | LS-C188425-100 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | 24F |
| Clone Type | monoclonal |
| Conjugation | PE |
| Description | CD86 antibody LS-C188425 is an RPE-conjugated mouse monoclonal antibody to rat CD86. Validated for Flow. |
| Recommended Dilution | FC (1:1) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 942 |
| Gene Symbol | CD86 |
| Immunogen | HTLV-1 transformed Lewis - S1 cells. |
| Isotype | IgG1 |
| Notes | CD86 antibody LS-C188425 is an RPE-conjugated mouse monoclonal antibody to rat CD86. Validated for Flow. |
| Alias Names | CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2 |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 100 tst |
| Source / Host | mouse |
| Species Reactivity | rat |
| Storage | 4°C |
| Substrate / Buffer | PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA |
| Technical Specifications | Recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86. |
| Product Page Updated | 2024-04-12T06:35:05.844Z |
| Volume | 100 tst |
