Article No
LS-C188326-0.5
CD47
CD47 antibody LS-C188326 is an unconjugated mouse monoclonal antibody to human CD47. Validated for Flow, IHC and IP.
Antibodies Primary
Specifications
| NCBI Number | 961 |
| Application | FC, IHC, IP |
| Article No | LS-C188326-0.5 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | 1/1A4 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | CD47 antibody LS-C188326 is an unconjugated mouse monoclonal antibody to human CD47. Validated for Flow, IHC and IP. |
| Recommended Dilution | FC (1:25 - 1:100) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 961 |
| Gene Symbol | CD47 |
| Immunogen | Human erythrocytes. |
| Isotype | IgG2b |
| Notes | CD47 antibody LS-C188326 is an unconjugated mouse monoclonal antibody to human CD47. Validated for Flow, IHC and IP. |
| Alias Names | CD47, CD47 antigen, CD47 molecule, Integrin associated protein, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6, Rh-related antigen, OA3, CD47 glycoprotein, IAP |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 0.5 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | -20°C |
| Substrate / Buffer | PBS |
| Technical Specifications | Specific for human CD47, also known as integrin-associated protein, a 50kD glycoprotein expressed on all hematopoietic cell lines, epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 is involved in several cellular processes including regulation of T cell and dendritic cell activation, regulation of neutrophil (PMN) chemotaxis, caspase-independent apoptosis, and may act as a signal transducer in the regulation of cation fluxes across cell membranes. CD47 has been identified as a ligand for the inhibitory macrophage receptor known as signal regulatory protein alpha (SIRPalpha) and as a receptor for thrombospondin-1. Cross-linking of CD47 with clone 1/1A4 co-stimulates the proliferation of T cells. |
| Product Page Updated | 2024-04-12T06:35:05.844Z |
