Article No
LS-C188262-0.1
CLEC7A / Dectin 1
Dectin 1 antibody LS-C188262 is an FITC-conjugated rat monoclonal antibody to mouse Dectin 1 (CLEC7A). Validated for Flow.
Antibodies Primary
Specifications
| NCBI Number | 64581 |
| Application | FC |
| Article No | LS-C188262-0.1 |
| Country Availability | SE, FI, DK, NO, FO, GL |
| Clone | 2A11 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/ml |
| Conjugation | FITC |
| Description | Dectin 1 antibody LS-C188262 is an FITC-conjugated rat monoclonal antibody to mouse Dectin 1 (CLEC7A). Validated for Flow. |
| Recommended Dilution | FC (1:1 - 1:10) |
| Supplier | LifeSpan Biosciences |
| Entrez Gene ID | 64581 |
| Gene Symbol | CLEC7A |
| Immunogen | Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1. |
| Isotype | IgG2b |
| Notes | Dectin 1 antibody LS-C188262 is an FITC-conjugated rat monoclonal antibody to mouse Dectin 1 (CLEC7A). Validated for Flow. |
| Alias Names | CLEC7A, BGR, CANDF4, CLECSF12, Dectin-1, DC-associated C-type lectin 1, DECTIN1, HDectin-1, Beta-glucan receptor, Lectin-like receptor 1, CD369 |
| Product Type | Antibodies Primary |
| Protocol | The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. |
| Purification | Protein G Purified |
| Shipping Information | RT |
| Size | 0.1 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 4°C |
| Substrate / Buffer | PBS, 0.09% Sodium Azide, 1% BSA |
| Technical Specifications | Recognizes murine beta-glucan receptor, also known as Dectin-1. Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macrophages via the protein tyrosine kinase known as Syk. Inhibits the binding of zymosan to macrophages via the beta-glucan receptor. The low endotoxin version is recommended for functional studies. |
| Product Page Updated | 2024-04-12T06:35:05.844Z |
