Article No
KBB-5TK37H-96
Horse equine BMP-2 ELISA Kit
Horse equine BMP-2 ELISA Kit (96 Tests). Quantitate Horse BMP2 in bone tissue, cell culture supernatants and serum. Sensitivity: 2pg/ml.
Assay & Detection
Specifications
| MW | 44702 MW |
| Additional Information | Bone morphogenetic protein-2(BMP-2, BMP 2A) belongs to the transforming growth factor beta(TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase(MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins(BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant horse equine BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa. |
| Application | ELISA |
| Article No | KBB-5TK37H-96 |
| Biosite Brand | Biosite ELISA |
| Country Availability | all |
| Conjugation | Unconjugated |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Description | Horse equine BMP-2 ELISA Kit (96 Tests). Quantitate Horse BMP2 in bone tissue, cell culture supernatants and serum. Sensitivity: 2pg/ml. |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 650 |
| Gene Symbol | BMP2 |
| Immunogen | Expression system for standard: CHO; Immunogen sequence: Q283-R396 |
| Notes | Horse equine BMP-2 ELISA Kit (96 Tests). Quantitate Horse BMP2 in bone tissue, cell culture supernatants and serum. Sensitivity: 2pg/ml. |
| Alias Names | Bone morphogenetic protein 2 ;BMP2 ; |
| Previous Article No | KBB-DB0E56 |
| Product Type | Assay & Detection |
| Protocol | 2000pg/ml,1000pg/ml, 500pg/ml, 250pg/ml, 125pg/ml, 62.5pg/ml, 31.2pg/ml |
| Range | 31.2 pg/ml - 2,000 pg/ml |
| Sample Type | Cell Culture, Serum, Tissue |
| Sensitivity | <2 pg/ml |
| Shipping Information | BLUE ICE |
| Size | 96wells/kit |
| Species Reactivity | horse/equine |
| Storage | -20°C, RT |
| Technical Specifications | Sandwich High Sensitivity ELISA kit for Quantitative Detection of horse equine BMP-2. 96wells/kit, with removable strips. |
| UniProt Number | C8C060 |
| Product Page Updated | 2024-04-17T08:14:24.385Z |
