Article No
HZ-1204-1000
VEGF121
HumanKine recombinant human VEGF121 protein
Proteins & Peptides
Specifications
| MW | 37 kDa, homodimer; 50 kDa, homotrimer, glycosylated |
| Additional Information | Animal-free Recombinant Human VEGF121 is expressed in human 293 cells as a glycosylated cytokine with an apparent molecular mass of 37 kDa as dimer and 50 kDa as trimer. Production in human 293 cells offers authentic glycosylation, contributing to stability in cell growth media. The cytokine is produced in a human cell expression system with serum free, chemically defined media. VEGF121 is a potent growth and angioenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis amd vascular permeability. |
| Article No | HZ-1204-1000 |
| Country Availability | SE, FI, DK, NO, EE, LV, LT |
| Description | HumanKine recombinant human VEGF121 protein |
| Supplier | Proteintech |
| Entrez Gene ID | 7422 |
| Format | 1x PBS, See Certificate of Analysis for details |
| Notes | This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulphide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells and is essential for physiological and pathological angiogenesis. Misregulations of this gene in mice result in abnormal embryonic blood vessel formation (PMID:10838264; 11329058). |
| Alias Names | L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGF121, VEGFA, VPF |
| Product Type | Proteins & Peptides |
| Purity | >95% |
| Shipping Information | ambient temperature |
| Size | 1000ug |
| Source / Host | human |
| Species Reactivity | human, pig/porcine |
| Storage | Store at -20°C~-80°C. |
| Substrate / Buffer | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). |
| Technical Specifications | This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulphide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells and is essential for physiological and pathological angiogenesis. Misregulations of this gene in mice result in abnormal embryonic blood vessel formation (PMID:10838264; 11329058). |
| Product Page Updated | 2024-03-01T15:48:56.946Z |