Article No
182-HIT302
Application | ELISA |
Article No | 182-HIT302 |
Country Availability | SE, FI, DK, NO, EE, LV, LT |
Description | LAL Chromogenic Endpoint Assay |
Supplier | Hycult biotechnology |
Additional Information | Bacterial endotoxin, like lipopolysaccharide (LPS), is a fever-producing by-product of gram-negative bacteria commonly known as pyrogen. |
Keywords | Inflammation & Cellular Damage |
Notes | Bacterial endotoxin, like lipopolysaccharide (LPS), is a fever-producing by-product of gram-negative bacteria commonly known as pyrogen. The principle of the test is based on the fact that bacteria cause intravascular coagulation in the American horseshoe crab, Limulus polyphemus. The agent responsible for the clotting phenomena resided in the crab's amoebocytes, or circulating blood cells, and that pyrogen (bacterial endotoxin) triggered the turbidity and gel-forming reaction enzymatically. Thus, endotoxin causes an opacity and gelation in Limulus amebocyte lysate (LAL), which is based on an enzymatic reaction. The simplicity and economy of the LAL chromogenic endpoint assay encourages the testing of various biologicals (including sera), devices, (air)filters and tissue culture medium for the presence of harmful levels of endotoxin. |
Previous Article No | HIT302, 182-HIT302 |
Product Type | Assay & Detection |
Range | The kit has a measurable concentration range of 0.04 to 10.0 EU/ml |
Research area | Microbiology |
Sensitivity | The kit has a minimum detection limit of 0.04 EU/ml. |
Shipping Information | Room Temperature |
Size | 3 plates |
Stability | Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least six months. |
Storage | Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least six months. |
Technical Specifications | The LAL assays are to be used for the in vitro quantitative determination of various biological fluids (including sera), devices, (air)filters and tissue culture medium. |
Product Page Updated | 2024-04-05T09:42:44.568Z |