Article No
GTX84890
Specifications
| Application | FC, ICC, IF |
| Article No | GTX84890 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 4H2 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | ALDH2 antibody [4H2] |
| Supplier | GeneTex |
| Entrez Gene ID | 217 |
| Gene Symbol | ALDH2 |
| Immunogen | Full length human recombinant protein of human ALDH2 (NP_000681) produced in HEK293T cell. |
| Isotype | IgG3 |
| Notes | This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq] |
| Product Type | Antibodies Primary |
| Protocol | ICC/IF: 1:100. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Affinity Purified |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| UniProt Number | P05091 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
