Article No
GTX84579
Specifications
| Application | FC, ICC, IF, IHC, WB |
| Article No | GTX84579 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 3H4 |
| Clone Type | monoclonal |
| Concentration | 0.69 mg/ml |
| Conjugation | Unconjugated |
| Description | eIF2 alpha antibody [3H4] |
| Supplier | GeneTex |
| Entrez Gene ID | 1965 |
| Gene Symbol | EIF2S1 |
| Immunogen | Full length human recombinant protein of human EIF2S1 (NP_004085) produced in HEK293T cell. |
| Isotype | IgG1 |
| Notes | Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:1000-1:2000. ICC/IF: 1:100. IHC-P: 1:50. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Affinity Purified |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | dog/canine, human, monkey, rat |
| Storage | 4°C, -80°C |
| UniProt Number | P05198 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
