Antibodies Primary

HIPPI antibody [2G3]

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HIPPI antibody [2G3]

Article No

GTX84311

Application

WB, ICC, IHC

Species Reactivity

human

Size

100μl

Clone

2G3

Source / Host

mouse

Product insert

Suggested protocols

Specifications

MW 49
Application WB, ICC, IHC
Article No GTX84311
Clone 2G3
Clone Type monoclonal
Concentration 0.71 mg/ml (Please refer to the vial label for the specific concentration.)
Conjugation Unconjugated
Description HIPPI antibody [2G3]
Supplier GeneTex Inc.
Entrez Gene ID 55081
Format Liquid
Immunogen Full length human recombinant protein of human IFT57 (NP_060480) produced in HEK293T cell.
Isotype IgG1
Localization Concentrates within the inner segment of cilia.
Notes Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator | however the relevance of such function remains unclear.
Alias Names Intraflagellar Transport 57,Esrrbl1,Hippi,Mhs4R2,Ofd18,Ift57
Product Type Antibodies Primary
Protocol WB: 1:2000.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications., ICC/IF: 1:100.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications., IHC-P: 1:50.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Purification Purified by affinity chromatography
Size 100μl
Source / Host mouse
Species Reactivity human
Storage Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4-8ºC. For long-term storage, aliquot and store at -20-8ºC or below. Avoid multiple freeze-thaw cycles.
Substrate / Buffer PBS pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Technical Specifications For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
UniProt Number Q9NWB7
Product Page Updated 2019-07-01T13:21:55.420Z

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