0.71 mg/ml (Please refer to the vial label for the specific concentration.)
HIPPI antibody [2G3]
Entrez Gene ID
Full length human recombinant protein of human IFT57 (NP_060480) produced in HEK293T cell.
Concentrates within the inner segment of cilia.
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator | however the relevance of such function remains unclear.
Intraflagellar Transport 57,Esrrbl1,Hippi,Mhs4R2,Ofd18,Ift57
WB: 1:2000.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications., ICC/IF: 1:100.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications., IHC-P: 1:50.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Purified by affinity chromatography
Source / Host
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4-8ºC. For long-term storage, aliquot and store at -20-8ºC or below. Avoid multiple freeze-thaw cycles.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
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